Windows 10 - The User Profile Service failed the sign-in Log in error
The User Profile Service failed the sign-in
User profile cannot be loaded
To fix this you will need to copy the "Default" user folder from a working PC to the broken one. Log into the PC with another accessible account. Rename or delete the old "default" user folder under C:\users (you will need to enable viewing of hidden files and folders). Copy from a working machine the "default" user folder from c:\users. Restart. Logging in should work now.
Settings for an External Relay in Exchange 2010
Create a new receive connector under Server Configuration" -> "Hub Transport". Set the Network tab to only receive mail from the host that will be relaying mail via your server (otherwise your server will relay spam). Set the "Authentication" tab to look like the following:
Test your connector via telnet